gene 1,804 words KG: IL30
Contents

IL30 — Interleukin 30 (p28 Subunit)

🧬 Gene Info
Gene SymbolIL30
Full NameInterleukin 30 (IL-27 p28 subunit)
Chromosome1p13.1
Functionencodes a secreted glycoprotein that plays critical roles in immune regulation, particularly in the context of neuroinflammation, autoimmunity, and potentially neurodegenerative diseases.
Primary ExpressionImmune cells, CNS microglia, astrocytes
Molecular Weight27 kDa
Amino Acids241 aa
Exons5
UniProt IDQ8TD97
NCBI Gene ID359710
GeneCardsIL30
Human Protein AtlasIL30
Protein ClassCytokine (IL-12 family member)
AliasIL27, p28, IL-27A
Associated DiseasesProstate Cancer
InteractionsIGF1, CXCL5, NFKB1
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (7)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.47
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.41
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.40

Related Analyses (4)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (11)

VEGFA — Vascular Endothelial Growth Factor A
gene · KG edge: expressed_in
TLR9 — Toll-Like Receptor 9
gene · KG edge: associated_with
SOCS3 - Suppressor of Cytokine Signaling 3
gene · KG edge: upregulates
PTEN Gene
gene · KG edge: expressed_in
PLG — Plasminogen
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

IL30 inhibits IGF1
IL30 inhibits CXCL5
IL30 upregulates SOCS3
IL30 inhibits Liver Injury
IL30 expressed_in Hepatocytes
IL30 associated_with Prostate Cancer
IL30 inhibits Cancer
IL30 data_in benchmark_ot_ad_answer_key:IL30
CD3 associated_with IL30
EGF expressed_in IL30