gene 2,561 words KG: ent-gene-0acda680
Contents

ANG — Angiogenin

🧬 Gene Info
Gene SymbolANG
Full NameAngiogenin
AliasesGene profile: ANG
Chromosome14q11.2
Protein TypeProtein
Functionis a multifunctional protein that plays critical roles in both physiological and pathological processes within the nervous system.
Molecular Weight14 kDa
Amino Acids147 aa
Exons2
PathwaysNF-κB
UniProt IDSearch UniProt
GeneCardsANG
Human Protein AtlasANG
Associated DiseasesCardiac, Heart Failure, Hypertension, Inflammation, Neuroinflammation
InteractionsActin, AGING, AKT, ANXA2, APOE, APOPTOSIS
KG Connections263 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (37)

Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.78
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Membrane Cholesterol Gradient Modulators
Score: 0.71
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
Flotillin-1 Stabilization Compounds
Score: 0.68
...
Score: 0.68
TREM2-Dependent Microglial Senescence Transition
Score: 0.62
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
APOE-Dependent Autophagy Restoration
Score: 0.89
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Aquaporin-4 Polarization Rescue
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
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Related Analyses (6)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · completed
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived

See Also (9)

Astrocytes
cell · KG edge: expressed_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: expressed_in
ACE Gene
gene · KG edge: implicated_in
ANXA2 — Annexin A2
gene · KG edge: activates
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: activates

Knowledge Graph (2 edges)

ent-gene-0acda680 data_in benchmark_ot_ad_answer_key:ANG
benchmark_ot_ad_answer_key:ANG data_in ent-gene-0acda680

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