gene 2,561 words KG: ANG 2026-03-24
kind:genesection:genesstate:published
Contents

ANG — Angiogenin

🧬 Gene Info
Gene SymbolANG
Full NameAngiogenin
AliasesGene profile: ANG
Chromosome14q11.2
Protein TypeProtein
Functionis a multifunctional protein that plays critical roles in both physiological and pathological processes within the nervous system.
Molecular Weight14 kDa
Amino Acids147 aa
Exons2
PathwaysNF-κB
UniProt IDSearch UniProt
GeneCardsANG
Human Protein AtlasANG
MutationLocation
K17ISignal peptide
Associated DiseasesCardiac, Heart Failure, Hypertension, Inflammation, Neuroinflammation
InteractionsKCNK2, NRP1, PIEZO1, PIEZO2, TNF, PDGFRB
KG Connections266 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (29)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.42
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.62
APOE-Dependent Autophagy Restoration
Score: 0.61
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59

Related Analyses (10)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed

See Also (9)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: activates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: expressed_in
Alzheimer Indonesia
institution · KG edge: expressed_in
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: activates

Knowledge Graph (12 edges)

ANG activates KCNK2
ANG inhibits KCNK2
ANG activates NRP1
ANG associated_with APOE
ANG protects_against SLC44A2
ANG activates PIEZO1
ANG activates PIEZO2
ANG activates TNF
ANG activates PDGFRB
ANG activates ATF3