gene 3,010 words KG: EFNB2 2026-03-27
kind:genesection:genesstate:published
Contents

EFNB2 — Ephrin B2

🧬 Gene Info
Gene SymbolEFNB2
Full NameEphrin B2
Protein TypeReceptor
Functionis a transmembrane ligand for the Eph family of receptor tyrosine kinases.
Molecular Weight38 kDa
Amino Acids333 aa
PathwaysCerebrovascular Development
Ensembl IDENSG00000145088
GeneCardsEFNB2
Human Protein AtlasEFNB2
Ephrin A ligands (EFNA1-5)GPI-anchored
Ephrin B ligands (EFNB1-3)transmembrane
Receptor-binding domaininteracts with Eph receptors
Conserved cysteine-rich regionmaintains structural integrity
Cleavage sitecan be proteolytically processed
Associated DiseasesCongenital Cerebrovascular Disease, Vein Of Galen Malformation
Known Drugs/CompoundsIcariin
InteractionsNFKB1, EPHB4, GFAP, GRB2
KG Connections28 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph