gene 1,135 words KG: ITPR1 2026-03-28
kind:genesection:genesstate:published
Contents

ITPR1 - Inositol 1,4,5-Trisphosphate Receptor Type 1

🧬 Gene Info
Gene SymbolITPR1
Full NameInositol 1,4,5-Trisphosphate Receptor Type 1
AliasesPage for ITPR1
Chromosome3p26.1
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight300 kDa
Amino Acids700 aa
Exons58
PathwaysCalcium Dysregulation
UniProt ID[Q14643](https://www.uniprot.org/uniprot/Q14643)
Ensembl IDENSG00000151952
GeneCardsITPR1
Human Protein AtlasITPR1
Chromosomal location3p26.1
Associated DiseasesDiabetes, stroke
KG Connections30 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.43
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.39

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

See Also (15)

Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: associated_with
WIPI1 Gene
gene · KG edge: associated_with
TIMP1 Gene
gene · KG edge: expressed_in
RB1CC1 Gene
gene · KG edge: associated_with
RAB7A — RAB7A, Member RAS Oncogene Family
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ITPR1 expressed_in MAP1LC3B
ITPR1 expressed_in TIMP1
ITPR1 associated_with WIPI1
ITPR1 activates stroke
ITPR1 inhibits stroke
ITPR1 implicated_in stroke
ITPR1 expressed_in GENES
ITPR1 expressed_in Atherosclerosis
ITPR1 expressed_in Autophagy
ITPR1 associated_with Diabetes