gene 722 words KG: GABARAPL2 2026-03-24
kind:genesection:genesstate:published
Contents

GABARAPL2 Gene

🧬 Gene Info
Gene SymbolGABARAPL2
Chromosome16q24.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues:
Molecular Weight~14 kDa
Amino Acids117 aa
Exons7 exons
PathwaysAutophagy
GeneCardsGABARAPL2
Human Protein AtlasGABARAPL2
FeatureDetails
Genomic CoordinatesGRCh38: Chr16: 88,547,407-88,565,432
Gene Length~18 kb
mRNA Length~1.2 kb
Protein Length117 amino acids
Associated DiseasesALS, Amyotrophic Lateral Sclerosis, Dementia, Diabetes, Frontotemporal Dementia
InteractionsSIRT5, BNIP3, PINK1, PARK2, MAP1LC3B, GABARAP
KG Connections127 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.43
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.39

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: regulates
GABARAPL1 — GABA Type A Receptor Associated Protein Lik
gene · KG edge: associated_with
GABARAP Gene
gene · KG edge: activates
CLN3 Gene - Ceroid Lipofuscinosis, Neuronal 3
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

GABARAPL2 activates SIRT5
GABARAPL2 activates BNIP3
GABARAPL2 activates PINK1
GABARAPL2 activates PARK2
GABARAPL2 activates MAP1LC3B
GABARAPL2 regulates SIRT5
GABARAPL2 associated_with P62
GABARAPL2 associated_with LC3
GABARAPL2 associated_with BECN1
GABARAPL2 associated_with PIK3C3