gene 1,671 words KG: KCNMA1
Contents

KCNMA1 Gene

🧬 Gene Info
Gene SymbolKCNMA1
Full NamePotassium Calcium-Activated Channel Subfamily M Alpha 1
AliasesBK channel, SLO1, KCa1.1
Chromosome10q22.3
FunctionLarge-conductance calcium-activated potassium channel (BK channel)
Molecular Weight126.0 kDa
Amino Acids1113
Exons28 exons spanning the coding sequence
PathwaysPotassium transport, Neuronal excitability
UniProt IDQ12791
Ensembl IDENSG00000156113
GeneCardsKCNMA1
Human Protein AtlasKCNMA1
Genomic Size~160 kb
Alternative SplicingMultiple splice variants generate channel diversity [1]
Associated DiseasesCancer
KG Connections103 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
Extracellular Matrix Stiffness Modulation
Score: 0.43

Related Analyses (3)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Anti-Tau Antibody vs ASO/Gene Therapy — Comparative Efficacy
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (8)

Hippo Signaling in 4R-Tauopathies
mechanism · KG edge: associated_with
KCNN4 — Potassium Calcium-Activated Channel Subfamily N
gene · KG edge: associated_with
KCNK2 Gene
gene · KG edge: associated_with
CFTR Gene
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

KCNMA1 associated_with TRPV1
KCNMA1 associated_with KCNN4
KCNMA1 associated_with KCNQ1
KCNMA1 associated_with CACNA1C
KCNMA1 associated_with SCN1A
KCNMA1 associated_with SCNN1A
KCNMA1 associated_with PIEZO2
KCNMA1 associated_with KCNK2
KCNMA1 associated_with Axon Guidance
KCNMA1 causes KCNQ1