| Gene Symbol | CACNA1C |
| Aliases | Page for Cav1.2 |
| Function | CACNA1C encodes the alpha-1C subunit of the L-type voltage-gated calcium channel (Cav1.2), one of the most important calcium channels in neurons and cardiac myocytes |
| Primary Expression | the brain, heart, and smooth muscle |
| Subcellular Localization | Somatodendritic compartment, dendritic spines, cardiac cells |
| Molecular Weight | 250 kDa |
| Pathways | Wnt signaling, oxidative stress response |
| UniProt ID | Q13936 |
| GeneCards | CACNA1C |
| Human Protein Atlas | CACNA1C |
| Drug | Use |
| Amlodipine | Hypertension, angina |
| Nifedipine | Hypertension |
| Verapamil | Arrhythmia, migraine |
| Nimodipine | Subarachnoid hemorrhage |
| Associated Diseases | Alzheimer, Anxiety, Cancer, Inflammation, Ms, psychiatric disorders |
| Interactions | CACNA1D, CACNA1E, CACNA1F, CACNA1G, CACNA1H, CACNA1I |
| KG Connections | 225 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |