gene 1,009 words KG: SCN5A 2026-03-24
kind:genesection:genesstate:published
Contents

SCN5A Gene

🧬 Gene Info
Gene SymbolSCN5A
Full NameSCN5A
Chromosome3p21
Protein TypeGene
Functionencodes a large transmembrane protein of 2016 amino acids forming the alpha subunit of the cardiac sodium channel.
Amino Acids2016 aa
Exons28
NCBI Gene IDSearch NCBI
GeneCardsSCN5A
Human Protein AtlasSCN5A
Associated DiseasesAging, Als, Alzheimer, Autism, Cancer, Carcinoma
KG Connections158 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
Extracellular Matrix Stiffness Modulation
Score: 0.43

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
EPAS1 Gene
gene · KG edge: associated_with
DRD2 Gene
gene · KG edge: therapeutic_target
CFTR Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

SCN5A associated_with TRPM7
SCN5A associated_with SCN1A
SCN5A associated_with TRPV4
SCN5A associated_with CACNA1B
SCN5A associated_with SCNN1A
SCN5A associated_with CFTR
SCN5A associated_with PIEZO2
SCN5A associated_with TRPA1
SCN5A associated_with KCNMA1
SCN5A associated_with TRPV1