gene 1,119 words KG: LATS2
Contents

LATS2

🧬 Gene Info
Gene SymbolLATS2
Full NameLarge Tumor Suppressor Kinase 2
Chromosome13q12.11
Protein TypeSerine/Threonine Kinase
Primary Expressionneural progenitor cells of the ventricular and subventricular zones, where it cooperates with LATS1 to restrict progenitor proliferati
Amino Acids1088 aa
Exons9
PathwaysNF-κB
Ensembl IDENSG00000150457
GeneCardsLATS2
Human Protein AtlasLATS2
Associated DiseasesBreast Cancer
InteractionsAPOPTOSIS, CANCER, ESR1, HIPPO, LATS1, MICRORNAS
KG Connections40 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Apoptosis in Neurodegeneration
entity · KG edge: activates
APC Gene
gene · KG edge: therapeutic_target
DISC1 — Disrupted in Schizophrenia 1
gene · KG edge: therapeutic_target
ESR1 — Estrogen Receptor Alpha
gene · KG edge: interacts_with
LATS1 — Large Tumor Suppressor Kinase 1, Hippo Pathway
gene · KG edge: activates

Knowledge Graph (12 edges)

LATS2 activates RAB27A
RAB27A activates LATS2
LATS1 activates LATS2
TAZ activates LATS2
TCF3 therapeutic_target LATS2
LATS2 therapeutic_target DISC1
LATS2 therapeutic_target TLR2
LATS2 therapeutic_target APC
LATS2 therapeutic_target POLE
LATS2 regulates Breast Cell Fate

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