gene 2,058 words KG: MID49
Contents

MID49 Gene

🧬 Gene Info
Gene SymbolMID49
Chromosome5q31.2
Functionis a mitochondrial outer membrane protein that plays a critical role in regulating mitochondrial dynamics.
Molecular Weight49 kDa
Amino Acids452 aa
PathwaysMitophagy
Ensembl IDENSG00000156535
GeneCardsMID49
Human Protein AtlasMID49
Mitochondrial quality controlRemoving damaged mitochondria through mitophagy
Energy distributionEnsuring equitable distribution of mitochondria throughout neurons
DNA maintenanceFacilitating mitochondrial DNA (mtDNA) mixing and repair
Apoptosis regulationControlling cytochrome c release
Associated DiseasesAls, Parkinson
InteractionsMFF, MID51, MIRO1, UBIQUITIN, DRP1, AMPK
KG Connections39 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (2)

Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.38
Mitochondrial Transfer Pathway Enhancement
Score: 0.44

Related Analyses (2)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (8)

Mitch A. Max
researcher · KG edge: regulates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: associated_with
MID51
gene · KG edge: associated_with
MFF Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

MID49 associated_with MIRO1
MID49 interacts_with MFF
MID49 interacts_with MID51
MID49 interacts_with MIRO1
MID49 regulates TOMM20
MID49 associated_with MFF
MID49 associated_with DRP1
MID49 activates UBIQUITIN
MID49 associated_with MID51
MID49 associated_with FIS1