gene 1,654 words KG: TOMM20 2026-03-21
kind:genesection:genesstate:published
Contents

TOMM20 — Translocase of Outer Mitochondrial Membrane 20

🧬 Gene Info
Gene SymbolTOMM20
Full NameTOMM20 — Translocase of Outer Mitochondrial Membrane 20
Chromosome5q33.1
Protein TypeGene
Functionis a gene located on chromosome 5q33.
Molecular Weight18 kDa
Amino Acids169 aa
PathwaysMitophagy
NCBI Gene ID98004
Ensembl IDENSG00000160948
GeneCardsTOMM20
Human Protein AtlasTOMM20
Associated DiseasesAging, Alzheimer, Cardiovascular, Ischemia, Melanoma, Parkinson
Known Drugs/CompoundsSpautin-1
InteractionsPTEN, USP30, FOXO3, HSPD1, COX4I1, GRIA2
KG Connections393 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (19)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Membrane Cholesterol Gradient Modulators
Score: 0.52
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51

Related Analyses (12)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: degrades
Alzheimer Indonesia
institution · KG edge: activates
AIM2 Inflammasome Modulation Therapy for Neurodegenerat
idea · KG edge: associated_with
ATG7 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TOMM20 regulates MAX
TOMM20 regulates MIRO1
TOMM20 regulates MID51
TOMM20 regulates MID49
TOMM20 regulates MFF
TOMM20 associated_with ATG7
TOMM20 associated_with GAPDH
TOMM20 associated_with PARK2
TOMM20 associated_with SQSTM1
TOMM20 associated_with BNIP3L