gene 1,072 words KG: MRAS 2026-03-27
kind:genesection:genesstate:publishedtopic:vascular-dementia
Contents

MRAS — Muscle RAS Oncogene

🧬 Gene Info
Gene SymbolMRAS
Full NameMuscle RAS oncogene
Chromosome3q22.3
Functionis a member of the RAS family of small GTPases located on chromosome 3q22.
Primary ExpressionSkeletal Muscle, Heart, Brain
Amino Acids188 aa
UniProt IDQ9Y4K0
NCBI Gene ID22808
Ensembl IDENSG00000145685
OMIM605432
GeneCardsMRAS
Human Protein AtlasMRAS
InteractionsSTAT3, VCP, INFLAMMATION, YAP, EGFR, HUWE1
KG Connections16 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
APOE Isoform Conversion Therapy
Score: 0.44
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54

Related Analyses (3)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Experiment: Multi-Ethnic PD GWAS
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (3)

Packard Center for ALS Research
institution · KG edge: inhibits
EGFR — Epidermal Growth Factor Receptor
gene · KG edge: inhibits
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (12 edges)

MRAS activates STAT3
MRAS interacts_with VCP
MRAS inhibits INFLAMMATION
MRAS inhibits Heart Failure
MRAS inhibits Cardiovascular
MRAS inhibits Inflammation
MRAS inhibits Diabetes
MRAS inhibits Stroke
MRAS inhibits Als
MRAS inhibits Hypertension