| Gene Symbol | NDUFAF7 |
| Full Name | NADH Dehydrogenase Complex Assembly Factor 7 |
| Function | Impaired complex I function leads to reduced ATP production and increased ROS, contributing to dopaminergic neuron vulnerability |
| GeneCards | NDUFAF7 |
| Human Protein Atlas | NDUFAF7 |
| Genetic susceptibility | Variants in complex I assembly genes including NDUFAF7 may increase susceptibility to sporadic PD |
| Mitochondrial dysfunction | Impaired complex I function leads to reduced ATP production and increased ROS, contributing to dopaminergic neuron vulnerability |
| PINK1/Parkin pathway | Damaged mitochondria with impaired complex I function are cleared through mitophagy, and defects in this pathway can lead to accumulation of dysfunctional mitochondria |
| Associated Diseases | Als, Alzheimer, Ms |
| Interactions | CANCER |
| KG Connections | 26 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |