gene 588 words KG: NDUFS1 2026-03-21
kind:genesection:genesstate:published
Contents

NDUFS1 Gene

🧬 Gene Info
Gene SymbolNDUFS1
FunctionThe NDUFS1 gene encodes NDUFS1 Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysOxidative Phosphorylation, Oxidative Stress
Ensembl IDENSG00000156510
GeneCardsNDUFS1
Human Protein AtlasNDUFS1
Associated DiseasesParkinson
InteractionsSNCA, SDHA, VDAC1, CYCS, NDUFS4, PARKINSON'S DISEASE
KG Connections77 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (9)

APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: therapeutic_target
NDUFS2 Gene
gene · KG edge: associated_with
LRPPRC — Leucine-Rich Pentatricopeptide Repeat Containi
gene · KG edge: causes
HSPA9 Gene
gene · KG edge: therapeutic_target
GLUD1 - Glutamate Dehydrogenase 1
gene · KG edge: causes

Knowledge Graph (12 edges)

NDUFS1 provides_data_for ds-83b31ef18d49
NDUFS1 therapeutic_target SDHA
NDUFS1 therapeutic_target CYCS
NDUFS1 therapeutic_target HSPA9
NDUFS1 causes LRPPRC
NDUFS1 therapeutic_target ACO2
NDUFS1 causes NDUFS2
NDUFS1 causes GLUD1
NDUFS1 therapeutic_target VDAC1
NDUFS1 therapeutic_target SNCA