gene 630 words KG: HSPA9 2026-03-24
kind:genesection:genesstate:published
Contents

HSPA9 Gene

🧬 Gene Info
Gene SymbolHSPA9
Chromosome5q31.2.
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionmost cell lines
Molecular Weight73.6 kDa
Amino Acids679 aa
PathwaysApoptosis, Oxidative Phosphorylation
Ensembl IDENSG00000113014
GeneCardsHSPA9
Human Protein AtlasHSPA9
Associated DiseasesParkinson
InteractionsTIMM22, HSPE1, OPA1, LAMP2, BNIP3L, SIRT1
KG Connections180 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (9)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.70
CYP46A1 Overexpression Gene Therapy
Score: 0.66
Senescence-Activated NAD+ Depletion Rescue
Score: 0.60
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.53
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: activates
cGAS-STING Pathway Dysregulation Hypothesis in Parkinso
hypothesis · KG edge: activates
GLI Gene Family
gene · KG edge: activates
FUNDC1 — FUN14 Domain Containing 1
gene · KG edge: inhibits

Knowledge Graph (12 edges)

HSPA9 expressed_in CYCS
HSPA9 expressed_in ACO2
HSPA9 therapeutic_target GLUD1
HSPA9 expressed_in SNCA
HSPA9 therapeutic_target LRPPRC
HSPA9 therapeutic_target NDUFS2
HSPA9 therapeutic_target NDUFS1
HSPA9 expressed_in SDHA
HSPA9 inhibits TIMM22
HSPA9 inhibits HSPE1