| Gene Symbol | LRPPRC |
| Full Name | Leucine-Rich Pentatricopeptide Repeat Containing |
| Chromosome | 2p21 |
| Function | LRPPRC encodes a leucine-rich pentatricopeptide repeat (PPR) protein that localizes to mitochondria and is involved in post-transcriptional regulation of mitochondrial gene expression. |
| Primary Expression | High in tissues with high mitochondrial content: brain, heart, skeletal muscle, kidney |
| Molecular Weight | ~156 kDa |
| Amino Acids | 394 aa |
| Exons | 38 |
| Pathways | Oxidative Phosphorylation |
| UniProt ID | Q9GZL0 |
| NCBI Gene ID | 90333 |
| Ensembl ID | ENSG00000138095 |
| OMIM | 607544 |
| GeneCards | LRPPRC |
| Human Protein Atlas | LRPPRC |
| Associated Diseases | Als, Parkinson |
| Known Drugs/Compounds | Duloxetine, Donepezil, donepezil |
| Interactions | ACO2, HSPA9, SNCA, SDHA, VDAC1, CYCS |
| KG Connections | 106 knowledge graph edges |
| Databases | GeneCardsHPASTRING |