gene 585 words KG: NDUFS2 2026-03-21
kind:genesection:genesstate:published
Contents

NDUFS2 Gene

🧬 Gene Info
Gene SymbolNDUFS2
FunctionThe NDUFS2 gene encodes NDUFS2 Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysOxidative Phosphorylation
Ensembl IDENSG00000147684
GeneCardsNDUFS2
Human Protein AtlasNDUFS2
Associated DiseasesParkinson
InteractionsSNCA, SDHA, VDAC1, CYCS, PARKINSON'S DISEASE, IMMUNE INFILTRATION
KG Connections69 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (8)

NDUFS1 Gene
gene · KG edge: associated_with
LRPPRC — Leucine-Rich Pentatricopeptide Repeat Containi
gene · KG edge: causes
HSPA9 Gene
gene · KG edge: therapeutic_target
GLUD1 - Glutamate Dehydrogenase 1
gene · KG edge: causes
CYCS
gene · KG edge: activates

Knowledge Graph (12 edges)

NDUFS2 associated_with NDUFS1
NDUFS2 therapeutic_target SDHA
NDUFS2 causes GLUD1
NDUFS2 therapeutic_target VDAC1
NDUFS2 therapeutic_target SNCA
NDUFS2 causes LRPPRC
NDUFS2 activates SNCA
NDUFS2 activates SDHA
NDUFS2 activates VDAC1
NDUFS2 activates CYCS