| Gene Symbol | NFH |
| Chromosome | 22q12.2 |
| Function | is a neuronal intermediate filament protein encoded by the NEFH gene on chromosome 22q12. |
| Molecular Weight | 200 kDa |
| Amino Acids | 816 aa |
| Exons | 4 |
| GeneCards | NFH |
| Human Protein Atlas | NFH |
| Condition | NfL Elevation |
| Multiple Sclerosis | Axonal injury marker, disease activity |
| Charcot-Marie-Tooth disease | Diagnostic, severity correlation |
| Creutzfeldt-Jakob disease | Rapidly rising NfL |
| Frontotemporal dementia | Differentiation from AD |
| Vascular dementia | Vascular burden indicator |
| ALS | ++ (very high) |
| Associated Diseases | Aging, Als, Alzheimer, Inflammation, Ms, Neurodegeneration |
| Interactions | KIF5B, PVALB, AKT1, RANK, P53, AGING |
| KG Connections | 96 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |