| Gene Symbol | OGDH |
| Full Name | Oxoglutarate Dehydrogenase |
| Chromosome | 7p13 |
| Protein Family | 2-oxoacid dehydrogenase family |
| Protein Type | Enzyme |
| Function | is a critical metabolic enzyme whose activity is significantly reduced in aging brain and in neurodegenerative diseases including Alzheimer's disease (AD) and Parkinson's disease (PD). |
| Gene Type | Protein-coding |
| Pathways | Lipid Metabolism |
| UniProt ID | Q02218 |
| NCBI Gene ID | 4967 |
| Ensembl ID | ENSG00000105953 |
| OMIM | 203740 |
| GeneCards | OGDH |
| Human Protein Atlas | OGDH |
| Neurotransmitter synthesis | Succinyl-CoA is a precursor for heme synthesis |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | DNA, GBA, LRRK2, MITOCHONDRIAL DYSFUNCTION, MTORC1, OGDHL |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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