gene 1,122 words KG: RAB1A
Contents

RAB1A — Ras-Related Protein Rab-1A

🧬 Gene Info
Gene SymbolRAB1A
Full NameRas-Related Protein Rab-1A
AliasesPage for RAB1A
Chromosome2p24.1
Functionis a member of the Rab GTPase family that regulates vesicle trafficking between the endoplasmic reticulum (ER) and Golgi apparatus [1](https://pubmed.
Subcellular Localizationspecificity</td>
Molecular Weight22 kDa
Amino Acids205 aa
UniProt IDP62820
NCBI Gene ID5876
Ensembl IDENSG00000100739
GeneCardsRAB1A
Human Protein AtlasRAB1A
Associated Diseasesneurodegeneration
InteractionsAUTOPHAGY, C9ORF72, ULK1
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (11)

Ubiquitin-Proteasome System Therapeutic Companies for P
company · KG edge: regulates
Amyotrophic Lateral Sclerosis
redirect · KG edge: regulates
Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: interacts_with
c9orf72-als-ftd-phenotype-mechanism
general · KG edge: interacts_with

Knowledge Graph (12 edges)

UBIQUITIN regulates RAB1A
RAB1A regulates P62
RAB1A interacts_with ULK1
RAB1A interacts_with C9ORF72
RAB1A regulates AMYOTROPHIC LATERAL SCLEROSIS
RAB1A interacts_with AUTOPHAGY
RAB1A regulates ALS
RAB1A regulates Als
RAB1A regulates Dementia
RAB1A regulates Amyotrophic Lateral Sclerosis

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