gene 2,463 words KG: SLC17A9
Contents

SLC17A9 Gene

🧬 Gene Info
Gene SymbolSLC17A9
Full NameSolute Carrier Family 17 Member 9
AliasesVNUT, CT64, ENT3, SLC17A9
Chromosome17q21.32
Protein TypeTransporter
Functionis a critical transmembrane protein responsible for the storage and release of nucleotides, particularly adenosine triphosphate (ATP), from secretory vesicles.
Molecular Weight52 kDa
Amino Acids477 aa
Exons14
Gene TypeProtein coding
PathwaysInflammasome
UniProt IDQ9NRH3 (SLC9A_HUMAN)
NCBI Gene ID131670
Ensembl IDENSG00000139233
GeneCardsSLC17A9
Human Protein AtlasSLC17A9
Associated Diseasesneurodegeneration
InteractionsP2X7, IL-1, Interleukin, Cytokine, Ras, INFLAMMATION
KG Connections30 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (13)

Microbial Inflammasome Priming Prevention
Score: 0.58
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Purinergic Signaling Polarization Control
Score: 0.55
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.47

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Related Experiments (5)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Mechanism: Progranulin Loss and TDP-43 Pathology in FTD
validation · proposed · Score: 0.40
TDP-43 PET Ligand Development for FTD and ALS
clinical · proposed · Score: 0.40

See Also (5)

Packard Center for ALS Research
institution · KG edge: activates
NLRP3 Inflammasome Hypothesis in Parkinson's Disease
hypothesis · KG edge: associated_with
Purinergic Receptor P2X 7 (P2X7)
gene · KG edge: activates
P2RX7 Gene
gene · KG edge: associated_with
ATP P2X3 Receptor Neurons
cell · KG edge: associated_with

Knowledge Graph (12 edges)

SLC17A9 associated_with NLRP3
SLC17A9 activates P2X7
SLC17A9 associated_with P2RX7
SLC17A9 transports P2RX7
SLC17A9 activates IL-1
SLC17A9 activates Als
SLC17A9 activates Inflammasome
SLC17A9 associated_with Neuron
SLC17A9 associated_with AND
SLC17A9 associated_with NEURON