| Gene Symbol | STEAP3 |
| Chromosome | 12. |
| Protein Type | Gene |
| Function | STEAP3 (Six-Transmembrane Epithelial Antigen of Prostate 3) encodes a metalloreductase that facilitates iron and copper uptake into cells. |
| Subcellular Localization | endosomal and plasma membranes, where it reduces extracellular and intracellular ferric iron to ferrous iron. This reduc |
| Pathways | Autophagy, Mapk |
| GeneCards | STEAP3 |
| Human Protein Atlas | STEAP3 |
| DMT1 (SLC11A2) | Iron transporter dependent on STEAP3-mediated reduction |
| Ferroportin (SLC40A1) | Iron exporter working |
| Associated Diseases | neurodegeneration |
| Interactions | AND, AUTOPHAGY, INFLAMMATION, JAK, MAPK, RAB7A |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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