| Gene Symbol | UHRF1 |
| Full Name | Ubiquitin-like with PHD and RING Finger Domains 1 |
| Chromosome | 19p13.3 |
| Function | UHRF1 is a key epigenetic regulator that bridges DNA methylation and histone modifications. |
| Primary Expression | cancers and has been implicated in neurodegenerative diseases including Alzheimer's and Parkinson's disease |
| Molecular Weight | 110 kDa |
| Amino Acids | 782 aa |
| Pathways | Nf-Κb |
| UniProt ID | Q96T23 |
| Ensembl ID | ENSG00000048828 |
| OMIM | 607909 |
| GeneCards | UHRF1 |
| Human Protein Atlas | UHRF1 |
| DNA Methylation Maintenance | Recruits DNMT1 to replication forks |
| Histone Binding | Reads histone modifications (H3K9me3) |
| Associated Diseases | neurodegeneration |
| Interactions | AMPK, ARG1, CYTOKINES, IL-1, IL-10, IL-4 |
| KG Connections | 38 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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