gene 649 words KG: DLC1 2026-03-24
kind:genesection:genesstate:published
Contents

DLC1 Gene - Deleted in Liver Cancer 1

🧬 Gene Info
Gene SymbolDLC1
AliasesPage for DLC1 Gene
Chromosome8p22.
FunctionDLC1 (Deleted in Liver Cancer 1) is a GTPase-activating protein (GAP) that specifically inactivates Rho family GTPases, primarily RhoA, Rac1, and Cdc42.
Primary Expressiondopaminergic neurons where it may protect against oxidative stress
PathwaysApoptosis, Wnt, Mapk
Ensembl IDENSG00000121667
GeneCardsDLC1
Human Protein AtlasDLC1
Associated Diseasesneurodegeneration
InteractionsKCNH1, NCAM1, RGS1, RAB27A, TLR4, TNC
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

DLC1 inhibits KCNH1
DLC1 inhibits NCAM1
DLC1 inhibits RGS1
DLC1 inhibits RAB27A
DLC1 associated_with COL4A1
DLC1 inhibits Carcinoma
DLC1 inhibits Ms
DLC1 inhibits Cancer
DLC1 inhibits Tumor
DLC1 inhibits Apoptosis