gene 3,221 words KG: WNT7A 2026-03-27
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:wnt-signaling
Contents

WNT7A Gene

🧬 Gene Info
Gene SymbolWNT7A
AliasesWnt Family Member 7A
Functionencodes a secreted signaling protein that belongs to the Wnt family — a group of highly conserved cysteine-rich glycoproteins essential for embryonic development, tissue homeostasis, and nervous sy...
Primary Expressionthe developing brain and spinal cord, where it:
PathwaysWNT, Wnt, Wnt signaling, Wnt Signaling
Ensembl IDENSG00000177283
GeneCardsWNT7A
Human Protein AtlasWNT7A
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsKCNK2, CD44, FGF10, KCNH1, NCAM1, RGS1
KG Connections46 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.44

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: inhibits
Packard Center for ALS Research
institution · KG edge: activates
TNC Gene
gene · KG edge: inhibits
PAK1 Gene
gene · KG edge: inhibits
NTRK2 Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

WNT7A associated_with LZTS1
WNT7A associated_with DCC
WNT7A inhibits KCNK2
WNT7A inhibits CD44
WNT7A inhibits FGF10
WNT7A associated_with DLC1
WNT7A inhibits KCNH1
WNT7A inhibits NCAM1
WNT7A inhibits RGS1
WNT7A inhibits RAB27A