gene 841 words KG: MBD2
Contents

MBD2 Gene - Methyl-CpG Binding Domain Protein 2

🧬 Gene Info
Gene SymbolMBD2
Full NameMethyl-CpG Binding Domain Protein 2
AliasesPage for MBD2 Gene, Page for MBD2 Protein
Chromosome18q21.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe brain with particularly high levels in:
Molecular Weight46 kDa
Amino Acids80 aa
UniProt IDQ9UBT4
NCBI Gene ID8932
Ensembl IDENSG00000134046
OMIM605078
GeneCardsMBD2
Human Protein AtlasMBD2
Methyl-CpG binding domain (MBD)Located at the N-terminus (amino acids 144-206), this ~80 aa domain confers specificity for methylated CpG dinucleotides
Associated DiseasesMs
InteractionsABCB1, KMT2A
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

MBD2 activates ABCB1
MBD2 activates KMT2A
ADRA2A expressed_in MBD2
DNMT3B expressed_in MBD2
DNMT1 expressed_in MBD2
DNMT3A expressed_in MBD2
PI3K expressed_in MBD2
ADRA2B expressed_in MBD2
MBD2 expressed_in AKT
MBD2 expressed_in MAPK14

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