gene 924 words KG: NGFR
Contents

NGFR Gene

🧬 Gene Info
Gene SymbolNGFR
Full NameNerve Growth Factor Receptor
Chromosome17q21.33
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
PathwaysNF-κB
UniProt IDP08151
NCBI Gene ID4800
Ensembl IDENSG00000164329
OMIM162010
GeneCardsNGFR
Human Protein AtlasNGFR
Survival signalingWhen co-expressed with Trk receptors, p75NTR enhances Trk signaling through:
Cell death signalingIn the absence of Trk receptors or when overexpressed, p75NTR can activate:
Associated DiseasesA1 astrocyte phenotype, Alzheimer, Neuropathy
InteractionsABCA7, ALZHEIMER, ALZHEIMER'S DISEASE, BDNF, CDH1, CTNNB1
KG Connections42 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Gamma Restoration Reduces Tau via Glymphatic Clearance
Score: 0.28

Knowledge Graph (12 edges)

NTRK2 interacts_with NGFR
SRC interacts_with NGFR
CTNNB1 interacts_with NGFR
STAT3 interacts_with NGFR
TRAF6 interacts_with NGFR
DISC1 interacts_with NGFR
NGFR interacts_with NTF4
CCT5 expressed_in NGFR
SPTLC1 associated_with NGFR
RAB7 associated_with NGFR

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