| Gene Symbol | NQO1 |
| Full Name | NAD(P)H Quinone Dehydrogenase 1 |
| Aliases | NAD(P |
| Chromosome | 16q22.1 |
| Protein Family | NAD(P)H dehydrogenase (quinone) family |
| Function | NQO1 uses NAD(P)H as an electron donor to reduce quinones, preventing the formation of toxic semiquinone radicals. |
| Primary Expression | Ubiquitous, high in brain, liver, kidney |
| Subcellular Localization | Cytoplasm, also nucleus (minor) |
| Molecular Weight | ~31 kDa |
| Amino Acids | 274 aa |
| Pathways | Apoptosis, Ferroptosis |
| UniProt ID | P15559 |
| NCBI Gene ID | 1728 |
| Ensembl ID | ENSG00000100119 |
| OMIM | 125860 |
| GeneCards | NQO1 |
| Human Protein Atlas | NQO1 |
| Associated Diseases | Inflammation, Senescence |
| Interactions | GCLC, TNF, PI3K, NRF2, AKT, KEAP1 |
| KG Connections | 280 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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