| Gene Symbol | ABCG2 |
| Full Name | ATP Binding Cassette Subfamily G Member 2 |
| Aliases | ABCG2PROTEIN |
| Chromosome | 4q22.1 |
| Protein Type | Transporter |
| Function | encodes a 72 kDa half-transporter that functions as a homodimer at the blood-brain barrier. |
| Molecular Weight | 72 kDa |
| Exons | 16 |
| Pathways | Akt, Apoptosis, Autophagy, Blood-Brain Barrier, Cell Cycle |
| Ensembl ID | ENSG00000118777 |
| GeneCards | ABCG2 |
| Human Protein Atlas | ABCG2 |
| Single transmembrane domain | Six α-helices |
| Nucleotide-binding domain | Located at the N-terminus (unusual for ABCG family) |
| Membrane topology | N-terminus extracellular, C-terminus intracellular |
| Associated Diseases | Alzheimer, Alzheimer's disease, Anxiety, Dementia, Depression |
| Interactions | ABCB1, AKT, AMPK, AND, ATP, AUTOPHAGY |
| KG Connections | 237 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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