protein 605 words KG: APOA1PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

APOA1 Protein

🔬 Protein Info
Gene SymbolAPOA1
Full NameApolipoprotein A1
ChromosomeChr11q23.3
FunctionThe APOA1 gene encodes Apolipoprotein A1, the primary protein component of high-density lipoprotein (HDL) particles.
Subcellular Localization</strong></td><td>Secreted, plasma HDL</td></tr>
UniProt IDP02647
NCBI Gene ID335
Ensembl IDENSG00000118137
OMIM107680
GeneCardsAPOA1
Human Protein AtlasAPOA1
Associated DiseasesAD, ALS, AMI, ARM, Alzheimer
InteractionsULK1, ATG5, EIF4EBP1, LC3, MTOR, ABCG1
KG Connections297 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (20)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Purinergic Signaling Polarization Control
Score: 0.55
Circadian Clock-Autophagy Synchronization
Score: 0.55

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in