| Gene Symbol | BNIP3 |
| Full Name | BCL2 Interacting Protein 3 |
| Chromosome | 10q26.3 |
| Protein Family | BH3-only Bcl-2 family |
| Function | is a pro-apoptotic BH3-only protein that plays a dual role in regulating both apoptosis and mitophagy. |
| Primary Expression | Ubiquitous; high expression in brain, heart, and skeletal muscle |
| Subcellular Localization | Mitochondrial outer membrane |
| Molecular Weight | 21.5 kDa |
| Pathways | Apoptosis, Autophagy, Chaperone, Histone Modification, Lipid Metabolism |
| UniProt ID | Q12986 |
| NCBI Gene ID | 664 |
| Ensembl ID | ENSG00000176171 |
| OMIM | 604488 |
| GeneCards | BNIP3 |
| Human Protein Atlas | BNIP3 |
| Associated Diseases | AD, ALI, ALS, Alzheimer, Carcinoma |
| Known Drugs/Compounds | dimethyl fumarate |
| Interactions | DISC1, EIF2S1, RIPK3, DRP1, CHOP, BECN1 |
| KG Connections | 1281 knowledge graph edges |
| Databases | GeneCardsHPASTRING |