| Gene Symbol | CAT |
| Full Name | Catalase |
| Chromosome | 11p13 |
| Protein Family | Catalase family (EC 1.11.1.6) |
| Protein Type | Enzyme |
| Function | Catalase is a tetrameric heme-containing enzyme that functions as one of the primary antioxidant defenses in cells. |
| Primary Expression | peroxisomes (primary location), cytosol and mitochondria, with highest levels in liver, kidney, and brain |
| Subcellular Localization | Peroxisomes, Cytoplasm |
| Molecular Weight | ~60 kDa (tetramer, 240 kDa total) |
| Pathways | Akt, Apoptosis, Autophagy, Epigenetic, Ferroptosis |
| UniProt ID | P04040 |
| NCBI Gene ID | 847 |
| Ensembl ID | ENSG00000121691 |
| OMIM | 115500 |
| GeneCards | CAT |
| Human Protein Atlas | CAT |
| Associated Diseases | AD, ADH, ALI, ALS, AMI, Aging |
| Known Drugs/Compounds | rapamycin |
| Interactions | OPTN, DNM1L, CANX, LGALS3, CALCOCO2, G3BP1 |
| KG Connections | 1394 knowledge graph edges |
| Databases | GeneCardsHPASTRING |