protein 914 words KG: CD36PROTEIN 2026-03-25
kind:proteinsection:proteinsstate:published
Contents

CD36 Protein (Cluster of Differentiation 36)

🔬 Protein Info
Gene SymbolCD36
AliasesComprehensive review of CD36 scavenger receptor
Chromosome7q21.11
Protein FamilyCD36 family (scavenger receptor class B)
Protein TypeGene
Functionis a multifunctional class B scavenger receptor encoded by the CD36 gene located on chromosome 7q21.
Subcellular LocalizationCell surface, endoplasmic reticulum, mitochondria (macrophages, microglia, platelets, adipocytes, neurons, endothelial cells)
Molecular Weight88 kDa
Amino Acids472 aa
Exons15
PathwaysAmyloid, Cholesterol, Epigenetic, Ferroptosis, Lipid Metabolism
UniProt IDP16671
GeneCardsCD36
Human Protein AtlasCD36
GeneCD36
Associated DiseasesALS, Alzheimer, Atherosclerosis, Cancer, Inflammation, Myocardial Infarction
InteractionsPLIN2, NR1H3, CMKLR1, SIRT6, NRF2, CX3CR1
KG Connections571 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

TREM2-Dependent Microglial Senescence Transition
Score: 0.86
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.83
TREM2-mediated microglial tau clearance enhancement
Score: 0.80
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.79
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (3)

Ketogenic diet fat threshold analysis in wild-type mice
validation · proposed · Score: 0.90
Protein expression analysis and cell migration assays in car
exploratory · proposed · Score: 0.88
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

Key Papers (1)

Assessment of the Spatial Distribution of Moisture Content in Granular
Sensors (Basel, Switzerland) 2024

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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