| Gene Symbol | CGASPROTEIN |
| Target Class | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Mechanism of Action | Small molecule inhibitor of cyclic dinucleotide synthesis |
| Subcellular Localization | , post-translational modifications, and interaction with regulatory proteins |
| Druggability | Medium (0.47) |
| Clinical Stage | Phase III |
| Molecular Weight | 57 kDa |
| GeneCards | CGASPROTEIN |
| Human Protein Atlas | CGASPROTEIN |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | cGAS Inhibitors, Aberrant DNA, RAPAMYCIN, Mitochondrial DNA, Ginkgetin, Mitochondrial Dna |
| Interactions | STING1, DNASE2, PARP1, IRF3, SQSTM1, RPS6KB1 |
| SciDEX Target | View Target Profile (4 clinical trials) |
| KG Connections | 1914 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |