| Gene Symbol | DNAJC6 |
| Full Name | DNAJC6 (Auxilin) |
| Aliases | Auxilin-1, Auxilin |
| Chromosome | 19q13.43 |
| Protein Type | Chaperone |
| Function | Unlike its close relative DNAJC5 (cystinosin), DNAJC6/Auxilin-2 is specifically expressed in neuronal tissues and regulates clathrin-mediated endocytosis[@roosen2014]. |
| Primary Expression | neurons throughout the brain, with particularly high levels in the substantia nigra, basal ganglia, and cerebral [cortex](/brain- |
| Molecular Weight | 70 kDa |
| Amino Acids | 935 aa |
| Exons | 15 |
| Pathways | Oxidative Stress |
| UniProt ID | Search UniProt |
| NCBI Gene ID | 9829 |
| Ensembl ID | ENSG00000138193 |
| GeneCards | DNAJC6 |
| Human Protein Atlas | DNAJC6 |
| Associated Diseases | Als, Alzheimer, Huntington, Ms, Parkinson, Parkinson's disease |
| Interactions | FBXO7, PINK1, PLA2G6, PRKN, SYNJ1, VPS13C |
| KG Connections | 137 knowledge graph edges |
| Databases | GeneCardsHPASTRING |