DJ1

Understanding Entity Pages

This page aggregates everything SciDEX knows about DJ1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DJ1 is a gene implicated in neurodegeneration research. Key relationships include: contributes to, associated with, causes. Associated with Inflammation, Ms, Neuroinflammation. Connected to 34 entities in the SciDEX knowledge graph.

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graph TD
    DJ1["<b>DJ1</b>"]
    Parkinson_s_Disease{"Parkinson's Disease"}
    DJ1 -->|"risk factor for"| Parkinson_s_Disease
    Parkinson_s_disease{"Parkinson's disease"}
    DJ1 -->|"associated with"| Parkinson_s_disease
    mitochondrial_dysfunction(["mitochondrial dysfunction"])
    DJ1 -->|"associated with"| mitochondrial_dysfunction
    Inflammation{"Inflammation"}
    DJ1 -->|"contributes to"| Inflammation
    Parkinson{"Parkinson"}
    DJ1 -->|"contributes to"| Parkinson
    Neuroinflammation{"Neuroinflammation"}
    DJ1 -->|"contributes to"| Neuroinflammation
    Ms{"Ms"}
    DJ1 -->|"contributes to"| Ms
    DJ1 -->|"protects against"| Inflammation
    DJ1 -->|"regulates"| Parkinson
    DJ1 -->|"protects against"| Ms
    DJ1 -->|"protects against"| Neuroinflammation
    GENES["GENES"]
    DJ1 -->|"associated with"| GENES
    VPS35["VPS35"]
    VPS35 -->|"associated with"| DJ1
    LRRK2["LRRK2"]
    LRRK2 -->|"associated with"| DJ1
    GENES -->|"associated with"| DJ1
    PINK1["PINK1"]
    PINK1 -->|"associated with"| DJ1
    PARKIN["PARKIN"]
    PARKIN -->|"associated with"| DJ1
    STING["STING"]
    STING -->|"activates"| DJ1
    NRF2["NRF2"]
    NRF2 -->|"activates"| DJ1
    NEURON["NEURON"]
    NEURON -->|"contributes to"| DJ1
    style DJ1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0