| Gene Symbol | HERC2 |
| Full Name | HECT and RLD Domain Containing E3 Ubiquitin Protein Ligase 2 |
| Chromosome | 15q13.1 |
| Protein Family | HERC family (HECT-type E3 ubiquitin ligases) |
| Function | is a hallmark of aging and neurodegenerative diseases. |
| Molecular Weight | 500 kDa |
| Amino Acids | 834 aa |
| Pathways | mTOR, mtor |
| UniProt ID | Q9Y5K5 |
| NCBI Gene ID | 8924 |
| Ensembl ID | ENSG00000128731 |
| OMIM | 607318 |
| GeneCards | HERC2 |
| Human Protein Atlas | HERC2 |
| RING finger domain | E3 ligase activity for substrate recognition |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | CANCER, INFLAMMATION, JAK2, LC3, STAT3, ULK1 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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