| Gene Symbol | HTR2CPROTEIN |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the central nervous system and plays diverse roles in mood regulation, appetite, sleep, cognition, and motor control |
| Subcellular Localization | ** | Cell membrane, caveolin-rich domains | |
| Molecular Weight | 70 kDa |
| GeneCards | HTR2CPROTEIN |
| Human Protein Atlas | HTR2CPROTEIN |
| N-terminal tail | Short extracellular sequence |
| Loop regions | Connect transmembrane helices |
| Seven α-helices | Cross the lipid bilayer |
| Conserved motifs | For ligand binding and G protein coupling |
| Orthosteric binding site | In the transmembrane core |
| C-terminal tail | Long intracellular tail with multiple phosphorylation sites |
| RNA editing site | A site in the coding sequence (positions 156, 157, 158) |
| Associated Diseases | Alzheimer, Alzheimer's disease, Anxiety, Autism, Bipolar |
| Interactions | CACNA1B, CACNA1H, DRD1, DRD2, GABRA1, GABRB2 |
| KG Connections | 134 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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