| Gene Symbol | LAMP2 |
| Aliases | Lysosomal-Associated Membrane Protein 2 |
| Chromosome | Xq24 |
| Protein Family | LAMP family |
| Function | LAMP2 encodes Lysosomal Associated Membrane Protein 2, a major lysosomal membrane glycoprotein essential for lysosomal function, autophagy, and chaperone-mediated autophagy (CMA). |
| Subcellular Localization | Lysosomal membrane |
| Molecular Weight | ~45 kDa (core), ~120 kDa (glycosylated) |
| Amino Acids | 410 aa |
| Pathways | Apoptosis, Autophagy, Chaperone, Lysosomal Degradation, Mtor |
| UniProt ID | P13473 (isoform A) |
| Ensembl ID | ENSG00000143106 |
| GeneCards | LAMP2 |
| Human Protein Atlas | LAMP2 |
| Protein Name | Lysosomal-Associated Membrane Protein 2A |
| Protein Length | 410 amino acids |
| Associated Diseases | ALS, APOPTOSIS, AUTOPHAGY, Alzheimer, Cancer |
| Known Drugs/Compounds | RAPAMYCIN, quercetin, rapamycin, statins |
| Interactions | PLIN3, BECN1, GRK2, FOXO1, NR1H3, MAP3K5 |
| KG Connections | 1123 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |