| Gene Symbol | MMP9 |
| Chromosome | 20q12-13 |
| Protein Family | Matrix metalloproteinase family |
| Protein Type | Protease |
| Target Class | Protease |
| Function | Small molecule zinc-chelating inhibitors or antibody-based inhibition |
| Mechanism of Action | Small molecule zinc-chelating inhibitors or antibody-based inhibition |
| Primary Expression | Secreted, extracellular space, neutrophil granules |
| Subcellular Localization | Extracellular, secreted |
| Druggability | Medium (0.54) |
| Clinical Stage | Phase III |
| Molecular Weight | 92 kDa (proenzyme), 82 kDa (active) |
| Amino Acids | 20 aa |
| Pathways | Akt, Apoptosis, Autophagy, Blood-Brain Barrier, Cell Cycle |
| UniProt ID | P14780 |
| GeneCards | MMP9 |
| Human Protein Atlas | MMP9 |
| Associated Diseases | ALI, ALS, AMI, Aging, Alzheimer |
| Known Drugs/Compounds | GENISTEIN, MMP9_IN1, IRN, Andrographis paniculata, MMP9-IN-1, Ginsenoside Rg2 |
| Interactions | MMP2, TRKB, TNF, TLR4, CD68, MTOR |
| SciDEX Target | View Target Profile (8 clinical trials) |
| KG Connections | 1730 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |