protein 2,115 words KG: PARK2PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

PARK2 Protein

🔬 Protein Info
Gene SymbolPARK2
Full NameParkin
AliasesPARK2PROTEIN
Chromosome6q26
Protein FamilyRBR family (Ring-Between-Ring) E3 ubiquitin ligases
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular LocalizationCytosol, mitochondrial outer membrane (upon activation)
Molecular Weight52 kDa
Amino Acids465 aa
Exons12
PathwaysApoptosis, Immune Response, Mitophagy
UniProt IDO60260
Ensembl IDENSG00000185345
GeneCardsPARK2
Human Protein AtlasPARK2
Associated DiseasesALS, Aging, Alzheimer, Alzheimer's disease, Cancer
Known Drugs/CompoundsTHSG, levodopa
InteractionsMAP1LC3B, PINK1, ATG5, LC3, TIMM17A, EIF2A
KG Connections502 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph