| Gene Symbol | STAT1 |
| Full Name | Signal Transducer and Activator of Transcription 1 |
| Aliases | Page for STAT1 Gene |
| Chromosome | 2q32.2 |
| Protein Type | Transcription Factor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 84 kDa |
| Pathways | cascade:
### Activation Mechanism, JAK-STAT signaling, JAK-STAT pathway |
| UniProt ID | P42224 |
| NCBI Gene ID | 6772 |
| Ensembl ID | ENSG00000115415 |
| GeneCards | STAT1 |
| Human Protein Atlas | STAT1 |
| Drug | Target |
| Tofacitinib | JAK1/2/3 |
| Associated Diseases | ALS, Autoimmune, Depression, Infection, Inflammation |
| Known Drugs/Compounds | berberine, valproic acid, Curcumin, metformin |
| Interactions | STAT3, TLR4, EGFR, JAK1, NRAS, ISG15 |
| KG Connections | 882 knowledge graph edges |
| Databases | GeneCardsHPASTRING |