protein 586 words KG: VEGFAPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

VEGFA Protein - Vascular Endothelial Growth Factor A

🔬 Protein Info
Gene SymbolVEGFA
Full NameVascular Endothelial Growth Factor A
AliasesPage for VEGFA Protein
FunctionVEGF exerts its effects by binding to receptor tyrosine kinases (VEGFR-1/Flt-1 and VEGFR-2/KDR/Flk-1) on endothelial cells and other cell types.
Subcellular Localization</th><td>Secreted, extracellular</td></tr>
Molecular Weight24 kDa
PathwaysAkt, Autophagy, Mapk, Oxidative Stress, Pi3K
Ensembl IDENSG00000112715
GeneCardsVEGFA
Human Protein AtlasVEGFA
Associated DiseasesAD, ALI, AMI, Aging, Als, Alzheimer
Known Drugs/Compoundsquercetin
InteractionsNRF2, NOS2, SMARCA4, SF3B1, APOB, TERT
KG Connections1026 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.48
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Retinal Vascular Microcirculation Rescue
Score: 0.54
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in