gene 561 words KG: UGCG
Contents

UGCG Gene

🧬 Gene Info
Gene SymbolUGCG
AliasesUDP-Glucose Ceramide Glucosyltransferase
FunctionThe UGCG gene encodes UDP-glucose ceramide glucosyltransferase (UGCG), also known as glucosylceramide synthase.
Primary Expressionglial cells including astrocytes and oligodendrocytes
Subcellular Localizationthe Golgi apparatus where it transfers glucose from UDP-glucose to ceramide. Dysregulation of glycosphingolipid metaboli
Molecular Weight46 kDa
PathwaysApoptosis, Nf-Κb, Oxidative Stress, Wnt, apoptosis pathway
Ensembl IDENSG00000165269
GeneCardsUGCG
Human Protein AtlasUGCG
Associated DiseasesAls
InteractionsAPOPTOSIS, CD63, CD9, ERK, OXIDATIVE STRESS, RAB35
KG Connections30 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Selective Glucosylceramide Synthase Inhibition with Lysosoma
Score: 0.00

Knowledge Graph (12 edges)

UGCG activates STING
CD63 activates UGCG
CD9 activates UGCG
RAB35 activates UGCG
UGCG activates RAB5
OXIDATIVE STRESS activates UGCG
ERK activates UGCG
UGCG activates Heart Failure
UGCG interacts_with Als
UGCG associated_with Sphingolipid

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