| Gene Symbol | RAB35 |
| Full Name | Ras-Related Protein Rab-35 |
| Aliases | Ras-Associated Protein 35 |
| Chromosome | 12q24.31 |
| Function | is a member of the Rab GTPase family that plays critical roles in regulating actin dynamics, endocytic trafficking, and synaptic vesicle recycling at presynaptic terminals. |
| Primary Expression | the brain, particularly in:
- Hippocampus: Highest expression in CA1-CA3 regions and dentate gyrus
- Cerebral cortex: Layer 2-4 pyramidal neur |
| Subcellular Localization | presynaptic terminals where it plays a central role in synaptic vesicle endocytosis and recycling. Following neurotransm |
| Pathways | Vesicle Cargo Routing, Vesicle Transport |
| UniProt ID | Q8WVM8 |
| NCBI Gene ID | 11020 |
| Ensembl ID | ENSG00000131721 |
| OMIM | 607352 |
| GeneCards | RAB35 |
| Human Protein Atlas | RAB35 |
| Protein Name | Ras-related protein Rab-35 |
| Associated Diseases | Als, Alzheimer, Ftd, Tauopathy |
| Interactions | UGCG, RAB5, TAUOPATHY, TAU PATHOLOGY, ALZHEIMER'S DISEASE, ALZHEIMER |
| KG Connections | 50 knowledge graph edges |
| Databases | GeneCardsHPASTRING |