gene 2,021 words KG: WIPI1
Contents

WIPI1 Gene

🧬 Gene Info
Gene SymbolWIPI1
AliasesWD Repeat Domain, Pyrin Interacting 1
Chromosome1p34.2
Protein TypeGene
FunctionWIPI1 localizes to the edges of the omegasome and is essential for the recruitment of downstream autophagy proteins (Proikas-Cezanne et al., 2004).
Molecular Weight49 kDa
Amino Acids449 aa
Exons10
PathwaysAutophagy, Mitophagy, autophagy pathway, ubiquitin-proteasome
GeneCardsWIPI1
Human Protein AtlasWIPI1
PhosphorylationMultiple serine/threonine phosphorylation sites regulate WIPI1 activity and localization
Associated DiseasesAls, Diabetes, Ms
InteractionsAMPK, ATG, ATG16L1, AUTOPHAGY, BECN1, ERK
KG Connections82 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

NDP52 recruits WIPI1
PARKIN interacts_with WIPI1
LC3 interacts_with WIPI1
NDP52 interacts_with WIPI1
PINK1 interacts_with WIPI1
ULK1 interacts_with WIPI1
P62 interacts_with WIPI1
WIPI1 interacts_with PARKIN
WIPI1 interacts_with NDP52
WIPI1 interacts_with LC3

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