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APP Swedish Mutation (APPswe)

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-diseases-app-swedish-mutation
Related Entities
diseases-app-swedish-mutation
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slugdiseases-app-swedish-mutation
entity_typemutation
kg_node_idNone
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Linked Artifacts (71)
mentions🧫Plasma ATN biomarkers across AD continuum in Chilean cohort80%
mentions🧫Creation and validation of 3xAD-ChAT-Cre mouse model80%
mentions🧫Adoptive transfer of TCRAβ-Tregs in AD mouse model80%
mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di75%
related🧫Plasma ATN biomarkers across AD continuum in Chilean cohort72%
related🧫Creation and validation of 3xAD-ChAT-Cre mouse model72%
related🧫Adoptive transfer of TCRAβ-Tregs in AD mouse model72%
mentions🧫Amyloid plaque load analysis in triple-mutant mouse brains70%
mentions🧫Comparison of free-text clinical reports vs Mini-ICF-APP str70%
mentions🧫Diosmin cognitive rescue in APP/PS1 mice70%
mentions🧫Behavioral assessment of APP/PSEN1/GD3S triple-mutant mice70%
mentions🧫Immunofluorescence analysis of cerebral microvascular densit70%
mentions🧫Chi3l1 deletion in APP/PS1 mouse model of Alzheimer's d70%
mentions🧫Transcriptomic profiling and differential expression analysi70%
mentions🧫AhR agonist effects on NEP in APP/PS1 mice70%
mentions🧫qPCR and western blot analysis of microvascular functional m70%
mentions🧫Anti-ASC antibody intracerebroventricular injection in APP/P70%
mentions🧫Proposed experiment from debate on Synaptic pruning by micro70%
mentions🧫s:** - Test MCU overexpression specifically in layer II neur70%
mentions🧫Proposed experiment from debate on Synaptic pruning by micro70%
mentions🧫Biomechanical Impact Profiles and Chronic Traumatic Encephal70%
mentions🧫Animal Model Comparison for Neurodegenerative Disease Therap70%
mentions🧫Down Syndrome Alzheimer's Disease: Mechanisms and Thera70%
mentions🧫Metal Ion Homeostasis Dysregulation in Alzheimer's Dise70%
mentions🧫Neural Stem Cell Therapy for Alzheimer's Disease70%
mentions🧫Prion Strain Diversity and Selective Vulnerability70%
mentions🧫Experiment Validation: In vitro ThT Assay70%
mentions🧫Microglial TREM2 Agonist In Vivo Efficacy70%
related🔬CRISPR-based therapeutic approaches for neurodegenerative di67%
related🧫Amyloid plaque load analysis in triple-mutant mouse brains63%
related🧫Comparison of free-text clinical reports vs Mini-ICF-APP str63%
related🧫Diosmin cognitive rescue in APP/PS1 mice63%
related🧫Behavioral assessment of APP/PSEN1/GD3S triple-mutant mice63%
related🧫Immunofluorescence analysis of cerebral microvascular densit63%
related🧫Chi3l1 deletion in APP/PS1 mouse model of Alzheimer's d63%
related🧫Transcriptomic profiling and differential expression analysi63%
related🧫AhR agonist effects on NEP in APP/PS1 mice63%
related🧫qPCR and western blot analysis of microvascular functional m63%
related🧫Anti-ASC antibody intracerebroventricular injection in APP/P63%
related🧫Proposed experiment from debate on Synaptic pruning by micro63%
related🧫s:** - Test MCU overexpression specifically in layer II neur63%
related🧫Proposed experiment from debate on Synaptic pruning by micro63%
related🧫Biomechanical Impact Profiles and Chronic Traumatic Encephal63%
related🧫Animal Model Comparison for Neurodegenerative Disease Therap63%
related🧫Down Syndrome Alzheimer's Disease: Mechanisms and Thera63%
related🧫Metal Ion Homeostasis Dysregulation in Alzheimer's Dise63%
related🧫Neural Stem Cell Therapy for Alzheimer's Disease63%
related🧫Prion Strain Diversity and Selective Vulnerability63%
related🧫Experiment Validation: In vitro ThT Assay63%
related🧫Microglial TREM2 Agonist In Vivo Efficacy63%
mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors60%
mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di60%
related🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors54%
related🔬CRISPR-based therapeutic approaches for neurodegenerative di54%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE Isoform Conversion Therapy50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying protein aggregation cross50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬How does metabolic reprogramming (glucose metabolism shifts,50%
mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa40%
mentions🔬What are the mechanisms underlying protein aggregation cross40%
mentions🔬How does metabolic reprogramming (glucose metabolism shifts,40%
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