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TMEM119 — Transmembrane Protein 119

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-tmem119

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Metadata

slug	genes-tmem119
entity_type	gene
kg_node_id	TMEM119

Linked Artifacts (85)

mentions🧫Proposed experiment from debate on Synaptic pruning by micro70%

mentions🧫Microglial Aging and Immune Memory in Neurodegeneration — Tr70%

related🧫Proposed experiment from debate on Synaptic pruning by micro63%

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see_also📖C1QC60%

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mentions🧪Metabolic Reprogramming via Microglial Glycolysis Inhibition50%

mentions🧪Senescent Microglia Resolution via Maresins-Senolytics Combi50%

mentions🧪Microglial Purinergic Reprogramming50%

mentions🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri50%

mentions🧪Microbiome-Derived Tryptophan Metabolite Neuroprotection50%

mentions🧫s:** - GPR32 knockout in microglia should worsen neuroinflam50%

mentions🧫Proposed experiment from debate on Synaptic pruning by micro50%

mentions🧫Microglial Aging and Immune Memory in Neurodegeneration — Tr50%

mentions🧫Microglial Contributions to Huntington's Disease Pathog50%

mentions🧫TREM2 Function in Alzheimer's Disease — From Risk Varia50%

mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%

mentions🧪Metabolic Reprogramming via Microglial Glycolysis Inhibition50%

mentions🧪Targeted Butyrate Supplementation for Microglial Phenotype M50%

mentions🧪Senescent Microglia Resolution via Maresins-Senolytics Combi50%

mentions🧪Microglial Purinergic Reprogramming50%

mentions🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri50%

mentions🧪Microbiome-Derived Tryptophan Metabolite Neuroprotection50%

mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%

mentions🧪Purinergic P2Y12 Inverse Agonist Therapy50%

mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%

mentions🧪TREM2-mediated microglial tau clearance enhancement50%

mentions🧪Optogenetic Microglial Deactivation via Engineered Inhibitor50%

mentions🧪APOE-TREM2 Interaction Modulation50%

mentions🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%

mentions🧪TREM2-Dependent Microglial Senescence Transition50%

mentions🧪Targeted Butyrate Supplementation for Microglial Phenotype M50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%

mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%

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related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬What are the mechanisms underlying what are the mechanisms b50%

related🔬What are the mechanisms underlying synaptic pruning by micro50%

related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%

related🔬What are the mechanisms underlying tdp-43 phase separation t50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬What are the mechanisms underlying what are the mechanisms b50%

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mentions📖GliaCure40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

mentions🔬What are the mechanisms underlying protein aggregation cross40%

mentions🔬What are the mechanisms underlying rna binding protein dysre40%

mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%

related🧪Metabolic Reprogramming via Microglial Glycolysis Inhibition40%

related🧪Senescent Microglia Resolution via Maresins-Senolytics Combi40%

related🧪Microglial Purinergic Reprogramming40%

related🧪Heat Shock Protein 70 Disaggregase Amplification40%

related🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri40%

related🧪Serine/Arginine-Rich Protein Kinase Modulation40%

related🧪Microbiome-Derived Tryptophan Metabolite Neuroprotection40%

mentions🔬What are the mechanisms underlying 4r-tau strain-specific sp35%

mentions🔬What are the mechanisms underlying neuroinflammation resolut35%

mentions🔬What are the mechanisms underlying what are the mechanisms b35%

mentions🔬What are the mechanisms underlying synaptic pruning by micro35%

mentions🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas35%