gene

als10

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about als10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections

0Hypotheses

0Analyses

8Outgoing

13Incoming

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	TARDBP
Full Name	TAR DNA-Binding Protein
Chromosome	1p36.22
Function	is a genetic locus associated with familial amyotrophic lateral sclerosis caused by mutations in the TARDBP gene (TAR DNA-Binding Protein).
Amino Acids	414 aa
Gene Type	Protein coding
UniProt ID	Q13148
NCBI Gene ID	23435
Ensembl ID	ENSG00000120910
OMIM	612069
GeneCards	TARDBP
Human Protein Atlas	TARDBP
Associated Diseases	ALS
Databases	GeneCards HPA STRING

🔮 Predicted Structure: als10 — AlphaFold Q13148 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (6)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    ALS10["ALS10"]
    ALS10 -->|"implicated in"| neurodegeneration["neurodegeneration"]
    ALS10 ---|"associated"| Als["Als"]
    ALS10 ---|"associated"| Glaucoma["Glaucoma"]
    ALS10 ---|"associated"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    ALS10 ---|"associated"| SOD1["SOD1"]
    ALS10 ---|"associated"| DNA["DNA"]
    ALS2["ALS2"] ---|"associated"| ALS10
    FIG4["FIG4"] ---|"associated"| ALS10
    FUS["FUS"] ---|"associated"| ALS10
    ALS8["ALS8"] ---|"associated"| ALS10
    ALSIN["ALSIN"] ---|"associated"| ALS10

Outgoing (8)

Target	Relation	Type	Str
Als	associated_with	disease	0.65
Glaucoma	associated_with	disease	0.65
Amyotrophic Lateral Sclerosis	associated_with	disease	0.65
SOD1	associated_with	gene	0.60
DNA	associated_with	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
GENE MUTATIONS	associated_with	gene	0.60
benchmark_ot_ad_answer_key:ALS10	data_in	dataset_row	0.00

Incoming (13)

Source	Relation	Type	Str
ALS2	associated_with	gene	0.60
FIG4	associated_with	gene	0.60
FUS	associated_with	gene	0.60
ALS8	associated_with	gene	0.60
ALSIN	associated_with	gene	0.60
ALS4	associated_with	gene	0.60
ALS9	associated_with	gene	0.60
TARDBP	associated_with	gene	0.60
ALS7	associated_with	gene	0.60
ALS	associated_with	gene	0.60
GENES	associated_with	gene	0.60
MOTOR NEURONS	associated_with	gene	0.60
benchmark_ot_ad_answer_key:ALS10	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

als10

Understanding Entity Pages

Wiki Pages (6)

ALS9 - Amyotrophic Lateral Sclerosis 9

ALS8 - Amyotrophic Lateral Sclerosis 8

ALS10 - Amyotrophic Lateral Sclerosis 10 (TARDBP)

ALS7 - Amyotrophic Lateral Sclerosis 7