gene

ano9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ano9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

45Connections

0Hypotheses

0Analyses

34Outgoing

11Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ANO9
Full Name	Anoctamin 9
Chromosome	11p15.5
Function	encodes a protein of 920 amino acids.
Primary Expression	epithelial tissues throughout the body, including lung, liver, kidney, and gastrointestinal tract, where it contributes to ion transport, cell volume
Amino Acids	920 aa
Pathways	Notch, Adaptive Immunity, Notch signaling, NOTCH
GeneCards	ANO9
Human Protein Atlas	ANO9
Associated Diseases	Dementia
KG Connections	39 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ANO9 — Anoctamin 9

gene · 2171 words

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Pathway Diagram

graph TD
    ANO9["ANO9"]
    ANO9 -->|"regulates"| Dementia["Dementia"]
    ANO9 -.biomarker for.-> TBK1["TBK1"]
    ANO9 -.biomarker for.-> Notch["Notch"]
    ANO9 -.biomarker for.-> Adaptive_Immunity["Adaptive Immunity"]
    ANO9 -->|"implicated in"| RBPJL["RBPJL"]
    ANO9 -->|"implicated in"| C3AR1["C3AR1"]
    ANO9 -->|"implicated in"| GENES["GENES"]
    C3AR1 -.biomarker for.-> ANO9
    GENES -.biomarker for.-> ANO9
    DNA["DNA"] -->|"regulates"| ANO9
    RBPJL -.biomarker for.-> ANO9
    UNC13A["UNC13A"] -->|"regulates"| ANO9
    FTLD["FTLD"] -->|"implicated in"| ANO9
    TBK1 -->|"implicated in"| ANO9

Outgoing (34)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ANO9	data_in	dataset_row	0.00
Dementia	implicated_in	disease	0.65
Dementia	regulates	disease	0.65
C3AR1	implicated_in	gene	0.60
UNC13A	implicated_in	gene	0.60
Rb	biomarker_for	protein	0.60
Neuron	regulates	cell_type	0.60
RBPJL	implicated_in	gene	0.60
RBPJL	biomarker_for	gene	0.60
C3AR1	biomarker_for	gene	0.60
Notch	biomarker_for	pathway	0.60
Adaptive Immunity	biomarker_for	pathway	0.60
GENES	implicated_in	gene	0.60
DNA	implicated_in	gene	0.60
DEMENTIA	implicated_in	gene	0.60
Notch	implicated_in	pathway	0.60
Adaptive Immunity	implicated_in	pathway	0.60
DEMENTIA	regulates	gene	0.60
DNA	regulates	gene	0.60
GENES	biomarker_for	gene	0.60
AND	biomarker_for	gene	0.60
NOTCH	biomarker_for	gene	0.60
TBK1	biomarker_for	gene	0.60
FTLD	implicated_in	gene	0.60
UNC13A	regulates	gene	0.60
TBK1	implicated_in	gene	0.60
Notch signaling	participates_in	pathway	0.60
Neuron	expressed_in	cell_type	0.55
FTLD	associated_with	concept	0.50
TBK1	associated_with	gene	0.50
RBPJL	associated_with	gene	0.50
VIPR1	associated_with	protein	0.50
C3AR1	associated_with	gene	0.50
NOTCH	associated_with	pathway	0.50

Incoming (11)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ANO9	data_in	dataset_row	0.00
TBK1	biomarker_for	gene	0.60
FTLD	implicated_in	gene	0.60
NOTCH	biomarker_for	gene	0.60
FTLD	biomarker_for	gene	0.60
C3AR1	biomarker_for	gene	0.60
RBPJL	biomarker_for	gene	0.60
UNC13A	regulates	gene	0.60
TBK1	implicated_in	gene	0.60
GENES	biomarker_for	gene	0.60
DNA	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity